In 1943 Albert Bechem introduced the “Principles of Radium and X-ray Dosage”, which is considered the first radioactive biological basis in treatment. Over time, thanks to the development of the fields of radiology biology and radiation metrology, radiotherapy has become an effective treatment for cancer therapy. However, like any other treatment, radiation therapy also causes unpleasant side effects in the patient, a barrier to interruption of treatment. In this article, let’s learn the side effects, ways to overcome them, and in which there is an extremely possible therapy is Betaglucan triterpen.
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Side effects of radiation therapy and how to reduce them:
Side effects will vary from patient to patient, and are difficult to predict depending on which part of the body is being treated. But will typically include:
- Fatigue: Usually starts with treatment and can last for a few weeks to a few months after treatment ends. To reduce fatigue you can: Rest more and ask a loved one to help with daily tasks, light exercise like walking but don’t overdo it. Supplement nutrients on the advice of health professionals so that healthy cells affected by radiation have a quick recovery energy source. Contact your healthcare professional if you suddenly feel very tired and have difficulty breathing. This may be a sign of a lack of red blood cells (anemia), which may require treatment.
- Burning and redness of the skin (like a sunburn) is sometimes dry and itchy in the irradiated area, they may appear 1-2 weeks after radiation therapy, notify your doctor for advice and how to handle it properly. Pay attention to keep the area of the injury clean to avoid infection.
- Hair Loss: Unlike chemotherapy hair loss, hair falls out only in areas that are irradiated. Hair may regrow several weeks after the end of radiation therapy or it may not regrow with high doses of radiation therapy. Ask your doctor about possible risks before radiation therapy!
- Eating problems: Mouth pain, loss of appetite, weight loss, discomfort when swallowing. You should avoid eating spicy, hot or spicy foods that can easily damage your mouth or esophagus, eat small meals, or eat liquid foods that are easy to swallow. If the problems are too serious, contact your doctor!
- Diarrhea: Diarrhea is a common side effect of radiation therapy to the abdomen or pelvis.
The side effect is not only the obsession of patients undergoing radiation therapy, it also increases the rate of treatment interruptions. A retrospective study published in the Asian Pacific Journal of cancer in 2020, conducted on 1476 cancer cases at Ahvaz Golestan Hospital, found that the rate of radiation treatment interruption due to side effects was 16.7%. – a not small number and is second only to machine problems (29.5%). Therefore, the control to reduce side effects will help increase the rate of patients completing treatment, thereby increasing the rate of successful treatment.
If there is a solution to correct errors, protect DNA, protect cells from the effects of irradiation, and enhance the stamina of healthy cells to withstand the adverse effects of radiation, it will be less. the unpleasant side effects that a patient has to endure, and can also contribute to improving treatment completion rates. Many studies have shown Betaglucan, Triterpen from Ganoderma lucidum is capable of doing that.
Beta Glucan Triterpen – Ganoderma lucidum superior solution helps reduce side effects of radiation therapy:
Betaglucan triterpen helps to reduce DNA damage, protect healthy cells, and reduce fatigue after radiation therapy.
The Cochrane Library – home to the most reliable scientific papers according to the Evidence Tower Medicine, in 2016 there was a composite review of more than 250 satisfactory studies on the topic of Ganoderma lucidum. in cancer treatment. In addition to the following key findings on the potential for increased response to treatment when combined with chemotherapy, the following benefits in reducing side effects from radiation therapy are shown:
- Ganoderma extract helps protect healthy cells, counteracts the effects of radiation on hematopoiesis by restoring hemoglobin and white blood cells, protecting cell membranes against lipid oxidation – a cause. damage to cell membranes.
Protects plasmids from genetic single and double strand breaks, reduces chromosomal abnormalities.
- Repair and repair of DNA chromosomes, prevent genetic instability leading to formation of carcinogenic factors.
- A few studies show that betaglucan helps increase wound healing, potential to aid in the recovery of skin damage caused by burns during irradiation.
In addition, when a combination of Ganoderma lucidum and Amifostine (a drug aimed at reducing cell destruction, reducing side effects due to radiation therapy, chemotherapy), it also helps to reduce the number of damaged healthy cells significantly.
Sissi Wachtel-Galor, John Yuen, John A. Buswell et al “Chapter 9 Ganoderma lucidum (Lingzhi or Reishi)” Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.
Jin X, Ruiz Beguerie J, Sze DMY, Chan GCF (2016) “ Ganoderma lucidum (Reishi mushroom) for cancer treatment(Review)” cochrane library.
jiezhong chena, robert seviour (2007) “Medicinal importance of fungal b-(1/3), (1/6)-glucans”mycological research 111,635-652.
Cuốn sách: Bệnh ung thư: nhận biết- dự phòng và chiến thắng, chủ biên GS.TSKH Nguyễn Khánh Trạch (chủ tịch Hội Nội khoa VN) và GS.TS Nguyễn Bá Đức (Phó CT Hội Phòng chống ung thư VN)