BETA GLUCAN, TRITERPENE EXTRACT FROM REISHI MUSHROOM TO RECOVER QUICKLY TO MULTIPLE AGENCIES

Side effects of the intangible common value make up the main weight and that is also the reason for the disruption such as delay, decreased vigilance or even cessation of value. Change in the value may be can be to the bottom of the level of the maximum is and easy-end Play, threatens computing or shortens the life of the patient. As such, multiple recovery systems are crucial in the chemotherapy process. The following article will analyze the benefits of Betaglucan Triterpen – Ganoderma in the work of rapid recovery of organs after chemotherapy.

1.Immune system

Chemotherapy is cancer method that is capable of weakening the immune system. Because the vocal cyst treats chemotherapy, the stick leads to adequate production of red blood cells, white blood cells and platelets. In particular, white blood cells (neutrophils) play a very important role in the immune system. Betaglucan, Triterpen – Linh Chi supports free system recovery with the following modes:

– Activate the endogenous immune system, adaptive: increased leukocytes index – host immunity: TCD3 (p <0.01), TCD4 (P <0.01), Leukocyte increase, NK cells, CD4 / CD8 ratio. (p <0.02) (1)

– Increased immune receptor mediators: significant increase in plasma concentrations IL-2, IL-6, IFN-g (p <0.05), significant decrease in IL-1 and TNF-a (p <0.05). Significantly increased number of CD56 + cells (p <0.05), CD3, CD4, CD8, NK cells (p <0.05) (2)

2. Liver

Cancer chemotherapy drugs can cause liver damage (especially cytarabines, filgrastim, hydroxyure and mercaptopurin) and these are shown on tests that have elevated liver enzymes and also increase the risk of toxicity. for body. Betaglucan Triterpen – Ganoderma lucidum has been shown to be effective in protecting the liver with the mechanism of improving antioxidant enzymes, significantly reducing the indexes of liver enzymes AST, ALT. (3) (4) 

Các chỉ số enzym gan trong huyết tương của khi bổ sung Betaglucan Triterpen – Linh chi  so với nhóm đối chứng (3)

3. Neurasthenia

Patients after cancer treatment may experience undesirable side effects on the nervous system such as: changes in thinking and cognition (impaired memory), impaired computing and problem solving. problem, dizziness, balance disorder, nausea, vomiting,….
Betaglucan Triterpen – Lingzhi improved and significantly outperformed the control group (without Betaglucan Triterpen – Lingzhi) in clinical improvement of symptoms in neurasthenia: reduction fatigue, nervousness, insomnia, anxiety (p = 0.002) (5)

4. Digestive system

The side effects of these chemicals can severely damage the intestinal lining cells. The intestinal immune system is also weakened, the patient may experience digestive disorders such as diarrhea or constipation, …
Betaglucan Triterpen aids in reducing side effects on the digestive system with these mechanisms:
  • Support to reduce nausea and vomiting caused by chemotherapy drugs (6)
  • Reduced lesion formation, ornithine decarboxylase (an enzyme that produces polyamine that stimulates damage healing) in the small intestine (7),(8)

5. Circulatory

Monitoring your blood cell count periodically is an important part of chemotherapy. This is because the drug can damage the cells in the bone marrow where blood cells are made. Chemotherapy can reduce red blood cells, white blood cells and platelets, thereby causing anemia, immune system and blood clotting.
Betaglucan Triterpen helps to protect red blood cells by limiting hemolysis, and inhibiting oxidation of red blood cell membranes. From there, it helps to reduce dizziness and fatigue caused by anemia.

When you have cancer, you must always adhere to the medical treatment of your doctor. Besides, the management of side effects is also extremely important during treatment. Betaglucan Triterpen supplement helps to recover quickly from chemotherapy, reduce chemotherapy interruptions due to side effects, do not miss the golden period treating your disease!

Source:

(1) Jin, X., Beguerie, J. R., Sze, D. M. Y., & Chan, G. C. (2016). Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database of Systematic Reviews, (6). (https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007731.pub3/abstract

(2) Gao, Y., Zhou, S., Jiang, W., Huang, M., & Dai, X. (2003). Effects of Ganopoly®(A ganoderma lucidum polysaccharide extract) on the immune functions in Advanced‐Stage cancer patients. Immunological investigations, 32(3), 201-215 (https://www.tandfonline.com/doi/abs/10.1081/IMM-120022979)

(3) Chiu, H. F., Fu, H. Y., Lu, Y. Y., Han, Y. C., Shen, Y. C., Venkatakrishnan, K., … & Wang, C. K. (2017). Triterpenoids and polysaccharide peptides-enriched Ganoderma lucidum: a randomized, double-blind placebo-controlled crossover study of its antioxidation and hepatoprotective efficacy in healthy volunteers. Pharmaceutical biology, 55(1), 1041-1046 (https://www.tandfonline.com/doi/full/10.1080/13880209.2017.1288750)

(4) Wu, J. G., Kan, Y. J., Wu, Y. B., Yi, J., Chen, T. Q., & Wu, J. Z. (2016). Hepatoprotective effect of ganoderma triterpenoids against oxidative damage induced by tert-butyl hydroperoxide in human hepatic HepG2 cells. Pharmaceutical biology, 54(5), 919-929 (https://www.tandfonline.com/doi/abs/10.3109/13880209.2015.1091481)

(5) Tang, W., Gao, Y., Chen, G., Gao, H., Dai, X., Ye, J., … & Zhou, S. (2005). A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia. Journal of medicinal food, 8(1), 53-58 (https://www.liebertpub.com/doi/abs/10.1089/jmf.2005.8.53)

(6) Wang, C. Z., Basila, D., Aung, H. H., Mehendale, S. R., Chang, W. T., McEntee, E., … & Yuan, C. S. (2005). Effects of Ganoderma lucidum extract on chemotherapy-induced nausea and vomiting in a rat model. The American journal of Chinese medicine, 33(05), 807-815. (https://www.worldscientific.com/doi/abs/10.1142/S0192415X05003429)

(7) Kashimoto, N., Ishii, S., Myojin, Y., Ushijima, M., Hayama, M., & Watanabe, H. (2010). A water-soluble extract from cultured medium of Ganoderma lucidum (Reishi) mycelia attenuates the small intestinal injury induced by anti-cancer drugs. oncology letters, 1(1), 63-68. (https://www.spandidos-publications.com/ol/1/1/63)

(8) Gao, Y., Zhou, S., Wen, J., Huang, M., & Xu, A. (2002). Mechanism of the antiulcerogenic effect of Ganoderma lucidum polysaccharides on indomethacin-induced lesions in the rat. Life sciences, 72(6), 731-745 (https://www.sciencedirect.com/science/article/pii/S0024320502023019)

(9) Oral Administration of Ganoderma lucidum to Lead-Exposed Rats Protects Erythrocytes against Hemolysis: Implicates to Anti-Anemia, Bangladesh (https://www.hindawi.com/journals/ecam/2015/463703/abs/)

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